As a result of improvement of the preparation procedure of tosyl-β-cyclodextrin in aqueous alkaline medium by the interaction of β-cyclodextrin with tosyl chloride (TosCl) at low temperatures, the yield of the target product was increased from 38% to 58%.
β-cyclodextrin, tosyl chloride, mono [6A-O- (4-tolylsulphonyl)]-β-cyclodextrin.
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